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Next-generation sequencing reveals clues to a parasite’s drug resistance

Leishmaniases are a complex of diseases caused by parasites that are transmitted by sandflies to an estimated 12 million people in 88 countries annually. In her latest evaluation, Microbiologist and...

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VIP prevents HIV

Two F1000 Faculty Members last month alerted us to some exciting news in the challenging sphere of HIV research. Led by Nobel Laureate David Baltimore, biologists at Caltech have been pioneering a new...

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World Malaria Day 2012

Today marks a crucial point in the global fight against the devastating malaria epidemic that has plagued humankind since we existed as a species. “Sustain gains, save lives, invest in malaria” forms...

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Gene gives insight into why the flu hits some people so much harder

So there’s a certain genre of movies in which a virus strikes a population. A large percentage of the population is quickly infected, people come back from the dead, chaos and looting ensue, etc....

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Why we are safe, for now, from avian flu

What would make avian influenza transmissible in humans? This is the question Yoshihiro Kawaoka and his team investigated in their much-anticipated study published in Nature earlier this year. The...

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Cell culture makes waves in HIV prevention

Cell culture has undoubtedly changed the face of biologic R&D over the past 30 years, and the vital role it plays has again been proven, this time allowing scientists from the Yale Cancer Center to...

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Milestones: 100,000 articles, 130,000 recommendations!

A double hit of exciting news: we’ve not only broken the 100,000-article barrier on F1000 Prime, but we’ve also published 130,000 recommendations! The 100,000th article was selected by Irini Sereti and...

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Thirty years since the announcement of HIV as the cause of AIDS

Since the first reports of AIDS, approximately 36 million people have died from the disease, with an estimated 35 million living with HIV. Drug therapy consists of HAART, highly active antiretroviral...

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Joep Lange

It is with great sadness that we note the tragic death of Professor Joep Lange, F1000Prime Section Head for HIV Infection & AIDS: Clinical, in the Malaysian Airline flight MH17 disaster yesterday....

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Ebola collection: sharing critical information faster

Beat Ebola with better research sharing, says the discoverer of virus. Continue reading →

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Featured F1000Prime Report: developing tools for malaria surveillance.

From this month’s batch of F1000Prime Reports, the peer-reviewed open-access review series on emerging themes in biology and medicine, we thought we’d feature a report dealing with one of the deadliest...

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Michelle Leach on Candida Albicans and thermo-pathogenicity

The fungal pathogen Candida albicans is one of the most persistent yeast pathogens known to man. Most people associate it only with thrush, but, as Michelle Leach explains in the video below, it is...

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World AIDS Day: Interview with Robert Gallo

Today is annual World AIDS Day: an opportunity for people worldwide to unite in the fight against HIV, show their support for people living with HIV and to commemorate people who have died. We spoke to...

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Informed consent in trials of genetically modified mosquitoes – an author and...

An Open Letter published by Pamela Kolopack, University of Toronto and James Lavery, Emory University, on Gates Open Research discussed issues around informed consent in field trials of genetically...

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Highlighting innovations and challenges for a TB-free world

The 24th March is annual World TB day, remembering Dr Robert Koch’s discovery of Mycobacterium tuberculosis on 24 March 1882. The day aims to increase public awareness of the tuberculosis (TB) epidemic...

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Finding a drug to treat Chikungunya virus

Miltefosine is a US Food and Drug administration (FDA) approved drug used to treat visceral leishmaniasis, commonly known as kala-azar, or black fever, which is a vector-borne disease transmitted by...

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Predicting flu vaccine effectiveness

Veljko Veljkovic, Biomed Protection, and Slobodan Paessler, Galveston National Laboratory, have published articles on F1000Research in which they predicted the effectivemess of the flu vaccine in...

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